SDEM3: NIOD’s most potent defence against environmental stressors.

As the world around us constantly evolves and we are exposed to more pollution, our skin is perpetually challenged. Each day, our skin cells takes a multitude of “hits” from free radicals, like pollutants, vehicle emissions, and smoke. Persistent exposure to these environmental stressors results in visible damage and premature ageing, which shows up on our skin as fine lines, wrinkles, dullness, uneven skin tone, increased dark spots and sagging skin.

At NIOD, we know that antioxidants are one of our skin’s best defences. We strive to constantly adapt to meet new demands our skin faces by evolving our products. Our latest offering uses ingredients incorporated in our skincare for the first time, and delivers antioxidant protection in higher concentrations.

That’s why we’ve spent the last 3 years formulating our latest offering from the lab–Superoxide Dismutase 3 Enzyme Mist (SDEM3).

What are Antioxidants & Why Does Your Skin Need Them?

NIOD Superoxide Dismutase 3 Enzyme Mist (SDEM3).

One might think of antioxidants as your body's insurance policy against environmental damage. They are like a savings account for your skin—starting early with regular deposits builds a strong reserve that you can draw from, when incidental expenses and unexpected emergencies take place. If you neglect to save or “protect” your skin early, you'll find yourself scrambling to cover the costs (damage) later. In this way, antioxidants work to protect our skin from damage caused by frequent exposure to stressors.

NIOD Superoxide Dismutase 3 Enzyme Mist (SDEM3).

Superoxide Dismutase 3 Enzyme Mist, an Antioxidant Powerhouse

Introducing Superoxide Dismutase 3 Enzyme Mist, a third generation product featuring antioxidants new to this formulation, which are important to support the skin’s defence abilities and prevent visible skin damage before it occurs.

It includes 4 new antioxidants including Superoxide Dismutase 3 (SOD3), a novel and newly isolated skincare ingredient in our skincare line that depletes with age but is an essential defensive antioxidant.

Understanding Superoxide Dismutase: Your Skin’s Built-In Defenders

Superoxide Dismutases (SODs) are a group of antioxidant enzymes that form the front line of defence against damaging environmental effects. There are 3 types of SOD enzymes that are naturally present within the skin. Scientific literature has demonstrated that as we age, the amount of SOD3 specifically declines; whereas the amount of SOD1 and SOD2 stay the same.

NIOD Superoxide Dismutase 3 Enzyme Mist (SDEM3).
NIOD Superoxide Dismutase 3 Enzyme Mist (SDEM3).

SOD3: A Newly Isolated Ingredient In Our Skincare

What makes SOD3 so unique is where this ingredient is positioned. Unlike SOD1 and SOD2 antioxidants that sit inside skin cells, SOD3 works between outer skin cells, where it’s better able to defend against collagen loss to help reduce the visible effects of environmental stressors on the skin. With age, as our body’s natural supply of SOD3 diminishes, so too does our skin’s ability to protect itself from external damage. This can lead to visible signs of ageing like fine lines, wrinkles and loss of firmness.

Prevent Visible Skin Damage Before it Occurs

Our Superoxide Dismutase 3 Enzyme Mist formulation supplements SOD3 and harnesses its power to help preserve collagen levels.

Its combined antioxidant technologies reinforce the skin’s protective barrier, which keeps irritants out and moisture in. The formulation:

  • Helps prevent collagen depletion, helps prevent premature signs of ageing and supports skin firmness.
  • Repairs visible wrinkles
  • Helps prevent skin damage caused by environmental irritants
  • Delivers instant hydration
  • Soothes visible redness, restoring radiance and tone
NIOD Superoxide Dismutase 3 Enzyme Mist (SDEM3).

Defence For The Future of Skin.

Launching 02.09.25, we encourage you to learn more and experience SDEM3 as a first line of environmental defence in your regimen, along with these other NIOD core products that support optimal skin ageing.

58.00 EUR

Targets
Signs of Aging

Suited to
All Skin Types

42.00 USD

Targets
Dryness

Suited to
All Skin Types

NIOD RE: Pigment (RP)
38.00 EUR

Targets
Uneven Skin Tone

Suited to
All Skin Types

53.00 EUR

Targets
Dryness

Suited to
All Skin Types

29.00 EUR

Targets
Uneven Skin Tone

Suited to
All Skin Types

67.00 EUR

Targets
Textural Irregularities

Suited to
All Skin Types

NIOD Survival 0 (S0)
25.00 EUR

Targets
Antioxidant Support

Suited to
All Skin Types

65.00 EUR

Targets
Crow's Feet

Suited to
All Skin Types

37.00 EUR

Targets
Signs of Congestion

Suited to
All Skin Types

87.00 EUR

Targets
Signs of Aging

Suited to
All Skin Types

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